BOLIVAR
| Date | Time | Opponent | Home-Away |
| 8/26/2022 | 7:00 PM | West Plains | Away |
| 9/2/2022 | 7:00 PM | Rolla | Away |
| 9/9/2022 | 7:00 PM | Parkview | Away |
| 9/17/2022 | 7:00 PM | Lebanon | Home |
| 9/23/2022 | 7:00 PM | Glendale | Away |
| 9/30/2022 | 7:00 PM | Camdenton | Away |
| 10/7/2022 | 7:00 PM | Waynesville | Home |
| 10/14/2022 | 7:00 PM | Hillcrest | Home |
| 10/21/2022 | 7:00 PM | Kickapoo | Home |
CAMDENTON
| Date | Time | Opponent | Home-Away |
| 8/26/2022 | 7:00 PM | Rolla | Away |
| 9/2/2022 | 7:00 PM | Kickapoo | Away |
| 9/9/2022 | 7:00 PM | Waynesville | Away |
| 9/16/2022 | 7:00 PM | Parkview | Home |
| 9/23/2022 | 7:00 PM | West Plains | Away |
| 9/30/2022 | 7:00 PM | Bolivar | Home |
| 10/7/2022 | 7:00 PM | Hillcrest | Away |
| 10/14/2022 | 7:00 PM | Lebanon | Home |
| 10/21/2022 | 7:00 PM | Glendale | Home |
GLENDALE
| Date | Time | Opponent | Home-Away |
| 8/26/2022 | 7:00 PM | Waynesville | Away |
| 9/2/2022 | 7:00 PM | West Plains | Home |
| 9/9/2022 | 7:00 PM | Rolla | Home |
| 9/16/2022 | 7:00 PM | Hillcrest | Away |
| 9/23/2022 | 7:00 PM | Bolivar | Home |
| 9/30/2022 | 7:00 PM | Lebanon | Away |
| 10/6/2022 | 7:00 PM | Parkview | Home |
| 10/14/2022 | 7:00 PM | Kickapoo | Home |
| 10/21/2022 | 7:00 PM | Camdenton | Away |
HILLCREST
| Date | Time | Opponent | Home-Away |
| 8/26/2022 | 7:00 PM | Kickapoo | Away |
| 9/2/2022 | 7:00 PM | Lebanon | Home |
| 9/8/2022 | 7:00 PM | West Plains | Away |
| 9/16/2022 | 7:00 PM | Glendale | Home |
| 9/23/2022 | 7:00 PM | Rolla | Home |
| 9/30/2022 | 7:00 PM | Waynesville | Away |
| 10/7/2022 | 7:00 PM | Camdenton | Home |
| 10/14/2022 | 7:00 PM | Bolivar | Away |
| 10/21/2022 | 7:00 PM | Parkview | Home |
KICKAPOO
| Date | Time | Opponent | Home-Away |
| 8/26/2022 | 7:00 PM | Hillcrest | Home |
| 9/2/2022 | 7:00 PM | Camdenton | Home |
| 9/9/2022 | 7:00 PM | Lebanon | Away |
| 9/16/2022 | 7:00 PM | Waynesville | Home |
| 9/23/2022 | 7:00 PM | Parkview | Away |
| 9/30/2022 | 7:00 PM | West Plains | Home |
| 10/7/2022 | 7:00 PM | Rolla | Away |
| 10/14/2022 | 7:00 PM | Glendale | Away |
| 10/21/2022 | 7:00 PM | Bolivar | Away |
LEBANON
| Date | Time | Opponent | Home-Away |
| 8/26/2022 | 7:00 PM | Parkview | Away |
| 9/2/2022 | 7:00 PM | Glendale | Away |
| 9/9/2022 | 7:00 PM | Kickapoo | Home |
| 9/17/2022 | 7:00 PM | Bolivar | Away |
| 9/23/2022 | 7:00 PM | Waynesville | Home |
| 9/30/2022 | 7:00 PM | Glendale | Home |
| 10/7/2022 | 7:00 PM | West Plains | Away |
| 10/14/2022 | 7:00 PM | Camdenton | Away |
| 10/21/2022 | 7:00 PM | Rolla | Home |
PARKVIEW
| Date | Time | Opponent | Home-Away |
| 8/26/2022 | 7:00 PM | Lebanon | Home |
| 9/2/2022 | 7:00 PM | Waynesville | Home |
| 9/9/2022 | 7:00 PM | Bolivar | Home |
| 9/16/2022 | 7:00 PM | Camdenton | Away |
| 9/23/2022 | 7:00 PM | Kickapoo | Home |
| 9/30/2022 | 7:00 PM | Rolla | Away |
| 10/6/2022 | 7:00 PM | Glendale | Away |
| 10/14/2022 | 7:00 PM | West Plains | Home |
| 10/21/2022 | 7:00 PM | Hillcrest | Away |
ROLLA
| Date | Time | Opponent | Home-Away |
| 8/26/2022 | 7:00 PM | Camdenton | Home |
| 9/2/2022 | 7:00 PM | Bolivar | Home |
| 9/9/2022 | 7:00 PM | Glendale | Away |
| 9/16/2022 | 7:00 PM | West Plains | Home |
| 9/23/2022 | 7:00 PM | Hillcrest | Away |
| 9/30/2022 | 7:00 PM | Parkview | Home |
| 10/7/2022 | 7:00 PM | Kickapoo | Home |
| 10/14/2022 | 7:00 PM | Waynesville | Away |
| 10/21/2022 | 7:00 PM | Lebanon | Away |
WAYNESVILLE
| Date | Time | Opponent | Home-Away |
| 8/26/2022 | 7:00 PM | Glendale | Home |
| 9/2/2022 | 7:00 PM | Parkview | Away |
| 9/9/2022 | 7:00 PM | Camdenton | Home |
| 9/16/2022 | 7:00 PM | Kickapoo | Away |
| 9/23/2022 | 7:00 PM | Lebanon | Away |
| 9/30/2022 | 7:00 PM | Hillcrest | Home |
| 10/7/2022 | 7:00 PM | Bolivar | Away |
| 10/14/2022 | 7:00 PM | Rolla | Home |
| 10/21/2022 | 7:00 PM | West Plains | Away |
WEST PLAINS
| Date | Time | Opponent | Home-Away |
| 8/26/2022 | 7:00 PM | Bolivar | Home |
| 9/2/2022 | 7:00 PM | Glendale | Away |
| 9/8/2022 | 7:00 PM | Hillcrest | Home |
| 9/16/2022 | 7:00 PM | Rolla | Away |
| 9/23/2022 | 7:00 PM | Camdenton | Home |
| 9/30/2022 | 7:00 PM | Kickapoo | Away |
| 10/7/2022 | 7:00 PM | Lebanon | Home |
| 10/14/2022 | 7:00 PM | Parkview | Away |
| 10/21/2022 | 7:00 PM | Waynesville | Home |
SPRINGFIELD CENTRAL
| Date | Time | Opponent | Home-Away |
| 8/25/2022 | 7:00 PM | Clever | Home |
| 9/2/2022 | 7:00 PM | Fair Grove | Away |
| 9/9/2022 | 7:00 PM | Cuba | Away |
| 9/16/2022 | 7:00 PM | Marionville | Home |
| 9/23/2022 | 7:00 PM | Strafford | Home |
| 9/30/2022 | 7:00 PM | Agape | Home |
| 10/7/2022 | 7:00 PM | Skyline | Away |
| 10/14/2022 | 7:00 PM | Buffalo | Away |
| 10/21/2022 | 7:00 PM | Forsyth | Away |
