Below is the Class 5 All-Region girls cross country team as voted on by the Southwest Cross Country Coaches Association.
| FIRST | ||||
| Klarie | Brown | Kickapoo | 12 | |
| Georgi | Carolus | Camdenton | 12 | |
| Kopelyn | Delong | Ozark | 12 | |
| Allie | Keizer | Joplin | 11 | |
| Gracie | Troester | Republic | 10 | |
| Ellie | Webb | Camdenton | 12 | |
| Chloe | Wood | Neosho | 10 | |
| Alexandria | Li | Central | 11 | |
| SECOND | ||||
| Isabella | Bateman | Kickapoo | 9 | |
| Maggie | Boyd | Carthage | 10 | |
| Charlotte | Cones | Kickapoo | 10 | |
| Cylee | Gilreath | Joplin | 12 | |
| Adelyn | Janssen | Nixa | 11 | |
| Riley | Kemna | Neosho | 11 | |
| Kristin | Probst | Republic | 11 | |
| THIRD | ||||
| Kaitlyn | Davis | Kickapoo | 10 | |
| LAINE | GARNER | Ozark | 10 | |
| Mackinzie | Harris | Nixa | 9 | |
| Jenna | Hefley | Nixa | 11 | |
| Ella | Johnson | Lebanon | 11 | |
| Misora | Nambara | Republic | 11 | |
| Erin | Seale | Nixa | 10 | |
| Lyla | Smith | Glendale | 9 | |
| Class 5 Runner of the Year: | Gracie Troester-Republic | |||
| Class 5 Coach of the Year: | Jeremy Goddard-Kickapoo | |||
